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Channel: Endpoints News

Supreme Court passes on Oklahoma’s drug middlemen spat

The US Supreme Court on Monday declined to take up a case that could have clarified the extent to which states can regulate pharmacy benefit managers without preempting federal law. The justices denied...

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Protagonist unveils 'triple-G' obesity pill, but human trials are nearly a...

Protagonist Therapeutics is a late entrant into the obesity space, but it cannot be accused of following the crowd. The California-based biotech unveiled its only obesity candidate, which is still in ...

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Exclusive: Bob Langer-founded Syntis Bio gets $33M Series A for obesity, rare...

A Boston biotech working on a different approach to oral obesity drugs collected a $33 million Series A, with plans to enter the clinic later this year, the company exclusively told Endpoints News....

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Beckley touts positive mid-stage psychedelic data, advancing atai merger

Beckley Psytech said its intranasal treatment bested a small-dose comparator in a Phase 2b trial of patients with treatment-resistant depression, notching another win for the burgeoning psychedelic...

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Unnatural Products taps argenx's help for ringed molecules, expands internal...

Unnatural Products has signed on argenx as its latest partner to take forward its approach to ringed molecules. Argenx will deliver unspecified upfront money in the double-digit millions to the Santa...

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Sama Fertility raises $3.8M to make IVF more accessible

Sama Fertility has raised $3.8 million to help people undergo IVF, mostly at home, Endpoints News learned exclusively. With seed funding, Sama is launching a program called SimpleIVF, which requires...

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Kevin Tang's Concentra snags another buyout, this time for IGM Biosciences

Kevin Tang is on a hot streak. Concentra Biosciences, the shell company from his hedge fund Tang Capital, has secured its fourth buyout of a struggling biotech so far in 2025. This time, Concentra is ...

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Advocates urge J&J to ‘put everything on the table’ for gene therapy despite...

For Lewis Winton, the world looks different from one eye. In the first few months after getting a gene therapy in his right eye, Winton kept covering his other eye with his hand. Winton, a ...

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Broad Institute conducts layoffs as it preps for cuts in federal funding;...

Plus, news about Bayer, Tempus AI, Apellis, Sobi, Nektar Therapeutics, Cybin, atai Life Sciences, HanchorBio, Henlius, Portal Biotech, Roche, AvenCell Therapeutics, Adagene and BerGenBio: Broad...

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The biggest health tech stories of 2025 — so far

We’re officially halfway through 2025. Rather than wait for the end of the year to reflect, the Health Tech team looked at our notebooks to see what transpired in the first six months of the ...

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AN Venture Partners lines up $200M freshman fund to champion Japanese innovation

At a time when few biotech venture capital firms are coming out of the gates, a Japan-focused investor is doing so and has closed a $200 million fund. AN Venture Partners, or ANV, initially ...

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PBM reforms fail to make Senate version of Trump's megabill

Efforts to rein in pharmacy benefit managers, for which drugmakers have been building bipartisan support over the years, were left out of the Senate-passed version of President Donald Trump’s megabill....

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Federal judge orders block on parts of HHS reorganization plan after states sue

A Rhode Island judge on Tuesday issued a preliminary injunction against parts of the Trump administration’s plan to restructure the federal health agencies. “The States have shown a likelihood of...

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Shionogi, BioVersys team up on ansamycin antibiotics in deal worth up to $614M

BioVersys is entering a pact with Shionogi to advance the Swiss biotech’s antibiotic program targeting non-tuberculous mycobacteria, with over half a billion dollars in biobucks on the line. Shionogi...

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Soriot mulls moving AstraZeneca stock listing to the US — report

AstraZeneca CEO Pascal Soriot is reportedly considering moving the company’s stock listing from the UK to the US. He also privately mooted the idea of changing the pharma company’s domicile, according...

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Organon stops work on drug once viewed as ‘game-changing’; NextPoint culls an...

Plus, news about ArriVent BioPharma, Everest Medicines, Ribocure, Paradigm Biopharmaceuticals, Verrica and Torii: Organon discontinues experimental therapy for endometriosis-related pain: The Merck...

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US investors divided on China's biotech rise

China’s ascent in drug development has kicked off debate among American investors over how to respond. Chinese companies are now competitive in some of the hottest areas of drug research, including...

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AbbVie cans oral ulcerative colitis drug from Landos buyout

AbbVie terminated work on the main drug from last year's $137 million buyout of Landos Biopharma. It's an abrupt end for ABBV-113, formerly known as NX-13, in ulcerative ...

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Vyne stops enrolling early-stage psoriasis study following clinical hold...

Vyne Therapeutics made several announcements Wednesday regarding its early-stage inflammatory disease asset, culminating in the decision to stop enrolling patients in a Phase 1b psoriasis study. It’s...

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After delay, Regeneron wins US approval of bispecific in multiple myeloma

At long last, Regeneron is bringing a bispecific antibody drug for multiple myeloma to the US market. The company said Wednesday that linvoseltamab was granted accelerated approval for adults with...

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CDC expands RSV vaccine recommendations, siding with previous panel of agency...

The CDC will recommend RSV vaccines for all at-risk adults in their 50s, expanding its current guidance on the shots and siding with the agency's former panel of vaccine experts. HHS Secretary Robert...

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AbbVie loses bid to block Tennessee's 340B contract pharmacy law

AbbVie failed to persuade a federal judge to block a recent Tennessee law that aims to regulate drugmaker discount policies under the federal 340B program. The decision is another blow to...

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Bristol Myers' China partner touts Phase 3 success for EGFRxHER3 bispecific ADC

Bristol Myers Squibb’s foray into cancer antibody-drug conjugates and bispecifics appears to be bearing fruit. Chinese startup Biokin, which partnered with Bristol Myers through its subsidiary...

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How FDA staff defied Prasad’s vaccine framework in Moderna review

Reviewers at the FDA recommended that Moderna’s next-gen Covid-19 vaccine be approved for all people 12 and older who previously received a shot, defying a new framework unveiled by agency leadership...

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